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Amanda Holden
Amanda Louise Holden (born 16 February 1971) is an English media personality, actress, television presenter, singer, and author. She has judged on the television talent show competition Britain's Got Talent since the show began its run in 2007 on ITV. As an actress, Holden played the role of Mel in Kiss Me Kate (1998–2000), Geraldine Titley in The Grimleys (1999-2001), Sarah Trevanion in Wild at Heart (2006–2008), Lizzie, the Ring Mistress, in Big Top (2009), and the title role in Thoroughly Modern Millie, for which she was nominated for a Laurence Olivier Award.
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Multiple sclerosis researcher swaps lab for great outdoors to complete huge charity challenge in Highland Perthshire

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dailyrecord.co.uk

A researcher whose findings could help create new treatments for multiple sclerosis (MS) is swapping the lab for the great outdoors to complete a huge charity challenge in Highland Perthshire this weekend.

Dr Irene Molina-González (34) will take on the Full Tilt Ultra during the Blair Castle Trail Weekender, near Pitlochry, tomorrow (June 4).Not only will Irene run 58km, but she will also summit two munros as part of the route – Càrn a’ Chlamain (963m) and Beinn Dearg (1009m).Irene, who ran the New York Marathon last year, will be taking part in the event with her partner Mario to raise funds for the MS Society.“Doing the research is rewarding but you want to do more,” Irene said. “You sometimes feel that you haven’t done enough.“Once you get to know MS you realise there are more people close to you that are affected by it.“You talk to people and they say ‘oh my friend’s mum’s got MS’ or ‘oh my uncle has got a brother with MS’ and I really want to help these people.“I want more people to keep doing research so that we can find treatments.”MS damages nerves in the body and makes it harder to do everyday things, like walk, talk, eat and think.As a researcher, Irene developed an interest in studying myelin – the protective coating around nerve fibres that is attacked and damaged by a person’s immune cells when they have MS.During Irene’s PhD, which was funded by the MS Society, she made discoveries about remyelination – the repair of damaged myelin – that could help with the development of new MS treatments.MS is relentless, painful and disabling.

Through her work, Irene has met people living with MS, including retired Paralympic swimmer and MS Society Ambassador Stephanie Millward MBE, who have helped her understand the

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