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“Battle Of Omicron” Being Won By New BA.4 And BA.5 Variants As Overlapping Covid Waves Hit U.S.

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Estimates released by the Centers for Disease Control and Prevention today indicate that the share of cases tied to Omicron variants BA.4 and BA.5 increased 79% in the past week.

That means, even as the more transmissible BA.2.12.1 Omicron subvariant became officially dominant in the U.S. last week, it’s already being pushed out by newcomers BA.4 and BA.5.

The result would seem to be overlapping waves of Omicron.While BA.2.12.1 gained an advantage by being more transmissible than BA.2 before it, the two newer variants are said to be making inroads at least in part because of their abilities to reinfect.“We now report findings from a systematic antigenic analysis of these surging Omicron subvariants,” says a recent paper published to the BioRxiv preprint server. “BA.2.12.1 is only modestly (1.8-fold) more resistant to sera from vaccinated and boosted individuals than BA.2.

On the other hand, BA.4/5 is substantially (4.2-fold) more resistant and thus more likely to lead to vaccine breakthrough infections.”If true, that means the new variants have a much larger population that they can potentially access via breakthrough infections, where previous variants like BA.2.12.1 produced far fewer breakthrough infections.The result has been what epidemiologist and biostatistician Dr.

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