Check out our 21/10 Atlético Madrid vs Manchester United prediction below Atlético Madrid and Manchester United meet for the first time in more than 30 years when they go head-to-head in the last 16 of the UEFA Champions League.
It is an opportunity for one of these struggling giants to inject some much needed impetus into their season but Atléti have major issues on the domestic front and Ralf Rangnick's side have a golden opportunity to take a big European scalp and get themselves into the quarter-finals.
There isn't much between these two from a betting perspective although Manchester United are narrow favourites at 3/4 with Grosvenor Sport to progress.
However, Diego Simeone's side are 29/20 favourites to win the first leg in the Wanda Metropolitano Stadium on Wednesday night.
Read more on manchestereveningnews.co.uk
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