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Grey's Anatomy: Everything You Need to Know About Alex and Izzie's Relationship

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tvguide.com
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Grey's Anatomy fans were thrown for a loop on Thursday when the show said goodbye to Alex Karev (Justin Chambers) by sending him off to go live with his ex-wife, Izzie (Katherine Heigl), and their two kids that he didn't know they had.

For OG Grey's fans, Izzie's impact on Alex is something embedded in our memory, but for those who have recently climbed aboard the Grey's train and aren't completely familiar with the dysfunctional couple's history, this article is for you.

Though, since it's been over 10 seasons since we've seen the two together, it also works as a refresher for Grey's Anatomy fans who don't remember exactly what went down between the two surgeons before Izzie left for good in Season 6.

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