BBC One show will see Perkins explore the truth about her orphaned grandfather and a great grandfather interned as an "enemy alien" during the First World War.
It was through filming another TV show during her career that Perkins first found out about her benign tumour which went on to cause "epic destruction" in her body.
Although non-cancerous and only the size of a grain of rice, it was the way she was told about the tumour and the way it was reported in the media after she had found out that made the ordeal all the more difficult for the star.
Speaking on Lorraine a few years ago about her tumour, which is located in her pituitary gland, Perkins said: "It was very difficult for me to see all those headlines.
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