Alex Karev city Seattle state Iowa show stars actress Love and Alex Karev city Seattle state Iowa

‘Grey’s Anatomy’ Stars Ellen Pompeo And Chris Carmack Pay Tribute To Justin Chambers After Karev’s Exit Explained

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Thursday’s “Grey’s Anatomy” finally resolved the mystery of Alex Karev’s abrupt departure from Grey Sloan Memorial after star Justin Chambers left the show after 16 seasons.

While his sudden exit was previously explained away by characters noting he was going to Iowa to be with his ailing mother, the truth was revealed — and it was a sweet blast from the past.

While Chambers didn’t appear in the episode, Karev did offer a voiceover to explain that he left Seattle — and his apparently soon-to-be-ex wife Jo (Camilla Luddington) — to reunite with his previous spouse, Izzie (Katherine Heigl).

Heigl also didn’t appear in the episode, which shouldn’t be surprising given the actress left the show years ago under less than amicable circumstances.

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