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Ellen Pompeo thanks fans as she becomes the last original Grey’s Anatomy star

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Ellen Pompeo has thanked Grey’s Anatomy fans after becoming the last-standing original cast member on the show. Justin Chambers signed off as Alex Karev in the medical drama on Thursday night (March 5, 2020), making Pompeo the last of the stars who first appeared on the series in 2005.

Not all fans were thrilled with the end of Karev’s story line after it was revealed he had left his wife and reunited with his ex, Izzie, played by Katherine Heigl, but Ellen appreciated the feedback about the pivotal episode. “Thank YOU!

You are truly the best most passionate most loyal fans anyone could ever ask for,” the actress wrote in a statement on Friday. “Because of you we got to make great tv… because of you we got to make television history!

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